HOOKE London, The headline 2025 longevity trend is a proactive, personalised approach. At the forefront of preventative health, HOOKE London uses advances in science and technology, data-driven insight, evidence-based strategies and expert guidance to help clients take control of their physical, mental, and cellular health. The goal is to improve the quality of their lives and support healthy ageing. 

Here are the top 10 trends the HOOKE’s experts identify as shaping client requests this year:

1. VO2 Max Testing – the Gold Standard for Cardiovascular Fitness
VO2 max is the gold standard for assessing cardiovascular fitness. It measures the maximum amount of oxygen the body can use during intense exercise and is performed at HOOKE’s Fitness facility on a treadmill or cycling ergometer. Higher VO2 max levels are associated with improved cardiovascular health, reduced risk of chronic diseases, and increased lifespan. It’s an essential marker for assessing aerobic capacity and is central to all of HOOKE’s assessments and membership plans.

2. Strength Training and Grip Strength – Critical Markers of Health and Independence
Muscle and grip strength are emerging as critical markers of long-term health and independence. Studies link greater grip strength to lower mortality rates and improved physical function in ageing populations. HOOKE’s bespoke fitness programmes, designed by expert trainers, physiotherapists, and podiatrists, ensure a targeted approach to strength-building and musculoskeletal resilience

3. Managing Chronic Inflammation to Decelerate Ageing 
Chronic low-grade inflammation, or “inflammaging”, is linked to various age-related diseases, including heart disease, diabetes, and Alzheimer’s. Managing inflammation is, therefore, crucial to decelerating the ageing process and for healthy ageing. HOOKE’s comprehensive blood testing panel measures various inflammation markers, including high-sensitivity C-reactive protein (hsCRP) – a much more sensitive version of the standard CRP test and more helpful in assessing chronic, low-grade inflammation.

4. Virtual Reality (VR) Therapy for Mental Health 
HOOKE London recognises that emotional and mental wellbeing are fundamental to extending health span and that Virtual Reality (VR) therapy can be a useful immersive tool to help manage stress, anxiety, and depression. Combined with biometric data analysis, such as heart rate variability, and psychological assessments, VR can build resilience while promoting emotional and cognitive wellness.

5. Wearables and Devices for Continuous Monitoring and Early Detection 
Health wearables like Whoop and Oura continuously track health metrics such as sleep quality, heart rate, and activity levels. HOOKE London incorporates real-time health feedback into their databases to monitor changes in members’ health, fitness, sleep and stress levels, detect emerging health issues and empower individuals to optimise their daily habits.

6. Contrast Therapy For Recovery Optimisation
Alternating between hot and cold exposure, such as saunas and ice baths, is gaining traction for its potential benefits in cellular repair, circulation improvement, and inflammation reduction. HOOKE London offers one of the only private recovery suites in Mayfair, providing a luxury environment for contrast therapy and recovery optimisation. 

7. Biological Age Calculators for Personalised Anti-Ageing Insights
Biological age calculators are transforming the way we understand ageing. HOOKE's Bioscore is a unique algorithm that combines insights from physical fitness, physiological markers, and emotional and cognitive health to give a personalised score that allows comparisons with others in the same age group, highlighting areas for improvement and guiding tailored strategies to slow the ageing process effectively.

8. Bloodwork for Personalised Supplementation 
Gone are the days of generic supplements. Based on bloodwork, personalised supplementation ensures individuals receive only the nutrients they need. HOOKE formulates tailor-made supplements to correct deficiencies and optimise health, ensuring clients receive the most effective nutritional support. 

9. The Rise of Low and Zero Alcohol Lifestyles
Growing awareness of the adverse health effects of alcohol (liver disease, cancer, and more) and the availability of socially appealing alternatives means increasing numbers of people are embracing a low or no-alcohol lifestyle. HOOKE London believes that while no alcohol is ‘healthy’, moderate to low alcohol consumption and low alcohol alternatives can be part of a broader commitment to balanced living without compromising health goals. 

10. Stem Cell Therapy for Joints and Inflammation
Umbilical-derived mesenchymal stem cells are being used to regenerate damaged tissue and reduce inflammation, particularly in joints. Their effectiveness is typically assessed through patient-reported outcomes, imaging, and inflammation marker reduction. Research suggests stem cell therapy may help slow the progression of degenerative joint conditions and chronic inflammation - both of which are linked to ageing and reduced quality of life. While this is a promising approach to regenerative medicine, treatments remain costly, difficult to access, and require further clinical validation. While HOOKE does not offer stem cell therapy directly, its team includes specialists in the field who can provide expert advice and access to treatment where appropriate.